Circular RNA (circRNA) is a unique type of non-coding RNA produced by back splicing of mRNA to form the covalent junction without 3’-5’ polarity and poly(A) tail. CircRNA was first discovered about 30 ...

Cancer is a complex disease that develops when cells in the body grow out of control. For many years, scientists have tried ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

It’s no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers that can be used for diagnosis and better ways to selectively get medicine ...

Using circular RNA, we’ve developed a platform we call isCAR™ for the in vivo delivery of CARs to immune cells. RNA is transient, but circular RNA, compared to linear mRNA, persists much longer in ...

The Mass General Brigham Gene and Cell Therapy Institute (GCTI) today announced it has launched the RNA Therapeutics Core, a first-of-its-kind, state-of-the-art facility and resource to advance the ...

On the left are three forms of the same RNA molecule, which is stabilised into a single form (on the right) by mitoxantrone. Ribonucleic acids (RNAs) serve as messengers between DNA and protein ...

Ribonucleic acid, commonly known as RNA, is involved in many biological functions, and some, including gene silencing, are utilized to cure diseases. RNA has recently gained attention as a promising ...