For the millions of people living with genetic diseases like muscular dystrophy and inherited liver disorders, one of the ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the ...

A research team has discovered an enhanced CRISPR gene-editing system that could enable targeted delivery inside the human ...

A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.

The new method relies on methyl groups, small chemical tags attached to DNA that regulate whether genes are on or off. This ...

Design by Evelyn Mousigian. Buy this photo. The CRISPR-Cas3 system, the focus of the U-M paper, is much less researched than Cas9. Despite this, Rackham student Mason Myers, one of the lead authors on ...

This review is designed by Professor Changyang Gong and written by his PhD student Shiyao Zhou. At the beginning, they elaborated the mechanism of CRISPR/Cas9 system. CRISPR/Cas9 system consists of ...

The CRISPR-Cas gene-editing system has long been the focus of research as a promising tool in genome editing. However, the emphasis has been on its underlying mechanisms and nucleases. In contrast, ...